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Calcium polystyrene sulfonate-induced gastrointestinal tract necrosis and perforation

Journal Volume 82 - 2019
Issue Fasc.4 - Letters
Author(s) P. Buraphat, S. Niyomnaitham, A. Pongpaibul, M. Maneerattanaporn
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(1) Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ; (2) Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ; (3) Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Hyperkalaemia is defined as a high serum potassium level requiring urgent and specific treatments to prevent life-threatening complications. Cation-exchange resin, such as calcium polystyrene sulfonate (CPS), promotes potassium excretion in the intestinal/colonic lumen and is a treatment of choice when less aggressive treatment is allowed (1). We herein present three cases of CPS- induced gastrointestinal tract necrosis or perforation.

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PMID 31950813